Critical Care Literature, Curated
The week’s most important critical care research.
Twenty-six high-impact journals across critical care, pulmonary, cardiac, anesthesia, and healthcare leadership — NEJM, JAMA, The Lancet, AJRCCM, CCM, CHEST, ICM, Circulation, JACC, BMJ Leader, and more — auto-tagged by the ICCN editorial calendar. Refreshed every six hours.
60 articles
Corrigendum to 'Comparison of Propofol-Based Total Intravenous Anesthesia versus Volatile Anesthesia with Sevoflurane for Postoperative Delirium in Adult Coronary Artery Bypass Grafting Surgery: A Prospective Randomized Single-Blinded Study', Journal of Cardiothoracic and Vascular Anesthesia, Volume 38, Issue 9, (2024), Pages 1932-1940
Preoxygenation when noninvasive ventilation is unavailable: positive pressure still matters
A small step for oxygenation, a giant leap for ICU liberation
Intercontinental VA-ECMO transfer from Reunion Island for access to heart transplantation and durable mechanical support: a 15-year experience
Reassessing Quetiapine in Obstructive Sleep Apnea
Reduction in Right Ventricular Afterload With Inhaled Nitric Oxide Predicts Survival in ARDS
When meta-analyses disagree: looking beyond the pooled estimate
Pulsatile Liver in Severe Tricuspid Regurgitation
New England Journal of Medicine, Ahead of Print. <br/>
Braking Bad News
New England Journal of Medicine, Ahead of Print. <br/>
Medical Standards by Federal Fiat
New England Journal of Medicine, Ahead of Print. <br/>
The Paradox of Medical Aid in Dying
New England Journal of Medicine, Ahead of Print. <br/>
[Obituary] Bernard Roizman
Virologist and world authority on herpes simplex virus. Born on April 17, 1929, in Chișinău, Romania (now in Moldova), he died in Chicago, IL, USA, on April 13, 2026, aged 96 years.
[Editorial] Who owns cardiometabolic disease?
A person with obesity, type 2 diabetes, chronic kidney disease, metabolic dysfunction-associated steatotic liver disease, and heart failure might receive five different diagnoses, attend five different clinics, and be managed according to…
[Perspectives] Tamzin Cuming: supporting inclusivity in surgery
When consultant colorectal surgeon Tamzin Cuming took part in a short film challenging prejudice about women in the workforce back in 2016, she had no idea what the reaction would be. Funded…
[Correspondence] Firearm violence exposure as an adverse childhood experience – Authors’ reply
We thank Diego A Díaz-Faes and colleagues for their interest in our Commission. Across two Lancet Commissions, we have called for investment in adolescent health and wellbeing.1,2 Adolescence is a key developmental…
[Correspondence] Newborn screening for birth defects in LMICs cannot wait
In low-income and middle-income countries (LMICs), gains in child survival reveal an important reality: birth defects account for a growing share of deaths among children younger than 5 years and cause substantial,…
[Perspectives] Wintering in Davos
Travel for health dates back to ancient times, but in the 19th century medical climatology emerged. The spa culture of the 18th century was largely displaced by a wider focus on the…
[Department of Error] Department of Error
Robb KA, Young B, Murphy MK, et al. Behavioural interventions to increase uptake of FIT colorectal screening in Scotland (TEMPO): a nationwide, eight-arm, factorial, randomised controlled trial. Lancet 2025; 405: 1081–92—In this…
[Department of Error] Department of Error
Coomarasamy A, Sindhu KN, Gallos I, et al. Postpartum haemorrhage: epidemiology, consequences, and missed opportunities. Lancet 2026; 408: 62–73—In this Series paper, data in table S7 of the appendix were incorrect and…
[Correspondence] Ecological integration for a legitimate and authentic One Health: a Hendra virus case study
Despite short-term costs to economic development, long-term human prosperity is not possible in an ecologically unstable planet. Efforts to preserve and stabilise ecosystems should function as public health measures with political and…
[World Report] Governance for artificial intelligence in health
Ministers have met in Lisbon, Portugal, to help decide how to ensure that artificial intelligence in health care is used safely and responsibly. Talha Burki reports.
[World Report] Health in the aftermath of Venezuela's earthquakes
Health and humanitarian systems are struggling to cope with the thousands of people injured and displaced. Joe Parkin Daniels reports.
[World Report] Health officials suspended over paediatric HIV infections
At least 78 children in Sindh, Pakistan, have been infected with HIV amid allegations of unsafe injection practices. Samaan Lateef reports.
[Department of Error] Department of Error
GBD 2023 Cancer Collaborators. The global, regional, and national burden of cancer, 1990–2023, with forecasts to 2050: a systematic analysis for the Global Burden of Disease Study 2023. Lancet 2025; 406: 1565–86—The…
[Correspondence] Firearm violence exposure as an adverse childhood experience
The second Lancet Commission on adolescent health and wellbeing outlined an agenda recognising adolescence as a key period for achieving lasting health improvements.1 Along with the 2025 Countdown to 2030 for women's,…
[Perspectives] Salim Yusuf: climbing mountains in cardiology
In the wide spectrum of human disease, the biggest killer, and the largest cause of premature death worldwide, is heart disease. The melioristic efforts to reduce this global burden form the focus…
Geographic differences in outcomes after emergency surgery in nonagenarians and centenarians admitted to intensive care in Australia: a population-based study
Introduction Methods Results Conclusion
Acute pulmonary embolism: clinical and echocardiographic recognition of normotensive shock
Validation of the ProVent mortality prediction model in patients receiving ≥ 7 days of mechanical ventilation
Supplemental Oxygen Use and High Intensity End-of-Life Healthcare Utilization in Older Adults with COPD
Neuroprognostication after cardiac arrest in patients without withdrawal of life-sustaining therapy: a prospective observational multicenter study
Background Methods Results Conclusions Trial registration
ICU-specific virtual reality for mental health after critical illness: an international three-arm randomized clinical trial
Background Methods Results Conclusions Trial registration
Sepsis-related immunosuppression: a comprehensive review of current research breakthroughs
Intraoperative hemoadsorption and cardiac surgery-associated acute kidney injury: an updated systematic review and meta-analysis with trial sequential analysis
Background Methods Results Conclusions Registration Graphical Abstract
Home mechanical ventilation for amyotrophic lateral sclerosis-a national study of survival and treatment trends across 27 years
Airing it out: What is driving chronic respiratory disease in rural America?
Validation of a Model Predicting Tracheostomy in Infants with Evolving Severe Bronchopulmonary Dysplasia
Strategies to Support and Effectively Implement the Proposed FDA Nicotine Standard: An Official American Thoracic Society Workshop Report
Clinical and Culture-Based Predictors of Gut Microbiome Alpha Diversity at the Time of ICU Admission
Beyond A and B: Exploring a Novel dynamic ECG change in Wellens Syndrome
PEEP Titration in Cardiogenic Shock: Impact on Congestion and Hemodynamic Phenotype
Left ventricular loading during femoro-axillary veno-arterial ECMO: the role of ECMO–cardiac flow interaction and aortic arch anatomy
Clearing the MIST: concurrent intrapleural tPA-DNase in pleural infection
Twelve-month outcomes of a multicenter cluster RCT on the impact of flexible ICU visitation on patients' mental health
A clue, a bystander, or both? Paraseptal emphysema at the intersection of smoking and interstitial lung abnormalities
Adaptive servo-ventilation for central sleep apnea: usage and effect on sleep and symptoms-a multicenter registry study
Corrigendum to: Positioning and Flow Effects on Lung Volume in Asymmetric High-Flow Nasal Cannula
Management of Heart Failure With Preserved Ejection Fraction: 2026 ACC Expert Consensus Decision Pathway: A Report of the American College of Cardiology Solution Set Oversight Committee
From Arterial Pressure to Tissue Perfusion: Blood-Pressure Targets after Resuscitated Infarction-Related Cardiac Arrest
Resuscitative Point-of-Care Ultrasound in Cardiac Arrest: Current Evidence and Clinical Applications
A New Standard in Muscle-Invasive Bladder Cancer — The End of the Cisplatin Era?
New England Journal of Medicine, Volume 395, Issue 4, Page 402-404, July 23, 2026. <br/>
Klebsiella Brain Abscess and Evolution of Heterovirulence in the Urinary Tract
New England Journal of Medicine, Volume 395, Issue 4, Page 408-410, July 23, 2026. <br/>
Daraxonrasib in Advanced RAS-Mutated Pancreatic Cancer
New England Journal of Medicine, Volume 395, Issue 4, Page 414-414, July 23, 2026. <br/>
Left Atrial Appendage Closure in Atrial Fibrillation
New England Journal of Medicine, Volume 395, Issue 4, Page 411-413, July 23, 2026. <br/>
More on Digital Twin–Guided Ablation for Ventricular Tachycardia
New England Journal of Medicine, Volume 395, Issue 4, Page 415-415, July 23, 2026. <br/>
Antiretroviral Therapy
New England Journal of Medicine, Volume 395, Issue 4, Page 374-387, July 23, 2026. <br/>
Breaking the RAS Barrier in Pancreatic Cancer
New England Journal of Medicine, Volume 395, Issue 4, Page 400-401, July 23, 2026. <br/>
Enfortumab Vedotin and Pembrolizumab in Cisplatin-Eligible Bladder Cancer
New England Journal of Medicine, Volume 395, Issue 4, Page 338-348, July 23, 2026. <br/>
Case 21-2026: A 28-Year-Old Man with Headache and Vision Loss in the Right Eye
New England Journal of Medicine, Volume 395, Issue 4, Page 389-398, July 23, 2026. <br/>
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