Wednesday · Cardiac & Hemodynamics
May 20, 2026
The Veins Are Telling You What the Arteries Cannot
Why VExUS Belongs in Every ICU’s Hemodynamic Vocabulary by 2026
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The ICCN Article Archive
Every Substack post, organised by ICCN's daily editorial themes. New summaries published every day — concise, evidence-based, built for the bedside.
Wednesday · Cardiac & Hemodynamics
Tuesday · Pulmonary & Mechanical Ventilation
May 19, 2026
Lung Protection Ends Where Drive Begins
The 2026 Case for Treating Respiratory Effort as a Vital Sign in the ICU
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Monday · Sepsis & Shock
May 18, 2026
Refractory Septic Shock Finally Has a Definition, and It Will Change How You Triage the Sickest Patient on Your Unit
Fifty-six experts. Twenty-two countries. Five Delphi rounds. Thirteen criteria. The phrase the bedside has been using for thirty years just got operational rules.
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Sunday · Leadership & Professional Development
May 17, 2026
Building a National Reputation in Critical Care Without an MD: The Seven Moves That Compound
A respiratory therapist, nurse, pharmacist, or APP who wants a national platform in critical care is being told to do the same things a physician would do, by people who…
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Saturday · General Critical Care
May 16, 2026
The Conservative Oxygen Hypothesis Is Dead. The Lesson Isn’t.
After UK-ROX added 16,500 patients to a literature already pointing in one direction, the trial-grade verdict on conservative oxygenation targets in unselected ICU adults is now unambiguous.
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Friday · Ethical AI in Healthcare
May 15, 2026
Five Rights, Zero Excuses: A Framework for Ethical AI in Critical Care Research
A discipline-specific framework for investigators, peer reviewers, and editors — before undisclosed AI use damages the trust that critical care depends on.
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Friday · Ethical AI in Healthcare
May 15, 2026
Pulse Oximetry Is the First Clinical AI. The Evidence Just Got Messier.
The 2025 FDA guidance was supposed to tighten the framework. The 2026 data muddied it. Reading both honestly is the most useful AI-literacy lesson a clinician will get this year.
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Thursday · Research & Evidence Mastery
May 14, 2026
ARDS Just Got a Bedside Phenotyping Test. The Trial That Matters Hasn’t Run Yet.
PHIND demonstrates that hyperinflammatory and hypoinflammatory ARDS can be separated in under an hour at the bedside — but feasibility is not yet evidence of benefit, and the field needs…
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Wednesday · Cardiac & Hemodynamics
May 13, 2026
What Your Hospital Reaches For First in Cardiogenic Shock Is Mostly About Where You Work
A new CCCTN registry analysis exposes how much of vasoactive selection in cardiogenic shock is institutional culture — and what the bedside team can do about it
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Tuesday · Pulmonary & Mechanical Ventilation
May 12, 2026
Mechanical Power Just Got an RT Workflow — and That’s the Story
A Mayo Clinic feasibility RCT shows that EHR-embedded, respiratory-therapist-driven mechanical-power-guided ventilation is implementable at the bedside without breaking workflow.
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Monday · Sepsis & Shock
May 11, 2026
Sepsis Just Got a Phenotype: What ImmunoSep Means for Your Monday Morning
A landmark JAMA trial shows two labs your hospital already runs — ferritin and monocyte HLA-DR — can match septic patients to the immunotherapy that helps them. The bedside implications…
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Sunday · Leadership & Professional Development
May 10, 2026
The Schedule Is the Strategy
What ICU leaders owe clinician-parents on the other 364 days — and the leadership artifact that exposes the gap.
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Saturday · General Critical Care
May 9, 2026
Reverse Triggering in 2026: Stop Asking If It's "Bad." Start Asking Which Phenotype You're Looking At.
A 2025 meta-analysis suggested it might be protective. A decade of physiology says it can pulverize the lung. Both are right — and the bedside answer is more demanding than…
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Friday · Ethical AI in Healthcare
May 8, 2026
The Scientific Record Is Broken. And AI Just Handed Us the Sledgehammer.
ICCN Substack | Friday Edition: Ethical AI in Healthcare
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Thursday · Research & Evidence Mastery
May 7, 2026
The Trial Said It Works. But Did You Actually Read It?
ICCN Substack | Thursday Edition: Research & Evidence Mastery
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Wednesday · Cardiac & Hemodynamics
May 6, 2026
Stop Treating Vasopressors Like Blood Pressure Glue
ICCN Substack | Wednesday Edition: Cardiac & Hemodynamics
Read on Substack →May 6, 2026
Stop Treating Vasopressors Like Blood Pressure Glue
ICCN Substack | Wednesday Edition: Cardiac & Hemodynamics
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Tuesday · Pulmonary & Mechanical Ventilation
May 5, 2026
Ventilator Liberation in 2026: The SBT Is Not the Finish Line. It Is the Starting Gun.
ICCN Substack | Tuesday Edition: Pulmonary & Mechanical Ventilation
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Monday · Sepsis & Shock
May 4, 2026
The Antibiotic Stewardship Paradox: In Sepsis, Giving Less Is Giving More — and the 2026 SSC Guidelines Just Made De-Escalation, Shorter Courses, and Procal-Guided Discontinuation the New Standard.
ICCN Substack | Monday Edition: Sepsis & Shock
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Sunday · Leadership & Professional Development
May 3, 2026
62% of Healthcare Professionals Have It. Most Will Never Name It. And the Clinicians Who Feel Like Frauds Are Almost Always the Best Ones on Your Team.
ICCN Substack | Sunday Edition: Leadership & Professional Development
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