Monday Edition

Sepsis & Shock

Every Monday: the literature that shapes the first hour.

Sepsis mortality remains stubbornly high — 25 to 40 percent in many cohorts. What happens in the first 60 minutes shapes the trajectory. Every Monday, ICCN publishes a bedside-ready summary on sepsis recognition, hemodynamic resuscitation, antibiotic strategy, and the new evidence that should change practice.

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What This Track Covers

Topics on the schedule.

Surviving Sepsis Campaign updates
Hour-1 bundle execution
Balanced crystalloids vs. saline
Norepinephrine first-line dosing
Antibiotic stewardship at the bedside
Septic cardiomyopathy & mixed shock
Lactate clearance & perfusion targets

Latest From This Track

Recent Monday editions.

Monday · Sepsis & Shock

July 20, 2026

After 15 Years of Walking Back Aggressive Fluid Resuscitation in Septic Shock, ARISE FLUIDS Delivers the Verdict: After Initial Fluid Loading, Either Strategy Works. Choose Based on the Patient.

The NEJM June 2026 randomized controlled trial enrolled 1,000 adults with septic shock across Australia and New Zealand emergency departments.

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Monday · Sepsis & Shock

July 13, 2026

The First Sixty Minutes: A Bedside Sequence for Sepsis and Septic Shock

The trials tell us what works.

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A Note from the Founder

Why Mondays matter.

Sepsis is the single most common reason for ICU admission worldwide, and the decisions made in the first hour are the highest-leverage decisions any clinician makes. Mondays bring rigorous, bedside-focused writing on the trials and guideline updates that change that hour.

— Javier Amador-Castaneda, BHS, RRT, FCCM, PNAP

Don’t Miss Mondays

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