Thursday Edition

Research & Evidence Mastery

Every Thursday: reading the literature the way it deserves to be read.

Research literacy is the foundation of bedside practice. The team that can read the literature beats the team that just hears about it. Every Thursday, ICCN publishes a deep-dive on a landmark trial, a methodology primer, or a critical appraisal of the latest publication moving practice.

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What This Track Covers

Topics on the schedule.

Landmark trial deep-dives
Critical appraisal frameworks (CASP, JAMA users’ guides)
Bayesian vs. frequentist reasoning
Subgroup analyses & their misuse
Composite endpoints & effect sizes
Network meta-analyses
Guideline interpretation & GRADE

Latest From This Track

Recent Thursday editions.

Thursday · Research & Evidence Mastery

June 4, 2026

Same p-Value, Different Certainty: How Bayesian Reanalysis Is Quietly Rewriting Critical Care Practice in 2026

The closing installment of our 3-week evidence appraisal trilogy.

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Thursday · Research & Evidence Mastery

May 28, 2026

The Fragility Index: Why 40 Percent of Critical Care RCTs Can Be Flipped by a Single Patient

One patient.

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A Note from the Founder

Why Thursdays matter.

Most clinicians read summaries of summaries. Thursdays at ICCN push deeper: the actual methods, the actual numbers, the actual judgments that separate a practice-changing study from one that should not have changed anything at all.

— Javier Amador-Castaneda, BHS, RRT, FCCM, PNAP

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